| 2021-11-06 | 13:00 | RC DIOK CO 1 | Amstelveense RC CO 1 | RC DIOK. LEIDEN | 6 - 19 |
| 2021-11-06 | 13:00 | RC Aachen CO 1 | CL Hilversum Panthers CO 1 | Schulenzentrum Handerweg. Aachen | 17 - 13 |
| 2021-11-06 | 13:00 | RC Eemland CO 1 | RC Groningen CO 1 | Sportpark De Bokkeduinen. AMERSFOORT | 17 - 12 |
| 2021-11-13 | 13:00 | CL Hilversum Panthers CO 1 | RC DIOK CO 1 | Sportpark Berestein. Hilversum | 26 - 7 |
| 2021-11-13 | 13:15 | RC Groningen CO 1 | RC Aachen CO 1 | Esserberg. HAREN | 53 - 19 |
| 2021-11-13 | 13:30 | Amstelveense RC CO 1 | RC Eemland CO 1 | Sportpark Sportlaan West. AMSTELVEEN | 47 - 14 |
| 2021-11-20 | 13:00 | Amstelveense RC CO 1 | CL Hilversum Panthers CO 1 | Sportpark Sportlaan West. AMSTELVEEN | 34 - 8 |
| 2021-11-20 | 13:00 | RC Eemland CO 1 | RC Aachen CO 1 | Sportpark De Bokkeduinen. AMERSFOORT | 48 - 28 |
| 2021-11-20 | 13:15 | RC DIOK CO 1 | RC Groningen CO 1 | RC DIOK. LEIDEN | 37 - 28 |
| 2021-12-11 | 13:00 | RC Aachen CO 1 | RC DIOK CO 1 | Schulenzentrum Handerweg. Aachen | afgelast |
| 2021-12-11 | 13:15 | RC Eemland CO 1 | CL Hilversum Panthers CO 1 | Sportpark De Bokkeduinen. AMERSFOORT | afgelast |
| 2021-12-11 | 13:15 | RC Groningen CO 1 | Amstelveense RC CO 1 | Esserberg. HAREN | afgelast |
| 2021-12-18 | 13:00 | RC DIOK CO 1 | RC Eemland CO 1 | RC DIOK. LEIDEN | afgelast |
| 2021-12-18 | 13:00 | CL Hilversum Panthers CO 1 | RC Groningen CO 1 | De Woerd. DRIEBERGEN | afgelast |
| 2021-12-18 | 13:30 | Amstelveense RC CO 1 | RC Aachen CO 1 | Sportpark Sportlaan West. AMSTELVEEN | afgelast |