| 2021-11-06 | 11:00 | Cas RC CU 1 | RC Bulldogs CU 1 | Sportpark Wouterland. CASTRICUM | 41 - 5 |
| 2021-11-06 | 11:00 | CL RCW/Zaandijk CU 1 | RC Hilversum CU 1 | PURMEREND | 12 - 10 |
| 2021-11-06 | 12:00 | RC Eemland CU 1 | CL Amsterdam CU 1 | Sportpark De Bokkeduinen. AMERSFOORT | 38 - 26 |
| 2021-11-13 | 11:00 | RC Hilversum CU 1 | RC Eemland CU 1 | Sportpark Berestein. Hilversum | 12 - 19 |
| 2021-11-13 | 11:00 | CL Amsterdam CU 1 | Cas RC CU 1 | De Eendracht. AMSTERDAM | 0 - 46 |
| 2021-11-13 | 12:30 | RC Bulldogs CU 1 | CL RCW/Zaandijk CU 1 | Fanny Blankers-Koen Sportpark. ALMERE | 45 - 0 |
| 2021-11-20 | 10:30 | CL RCW/Zaandijk CU 1 | CL Amsterdam CU 1 | SPORTPARK JAGERSVELD. ZAANDAM | 44 - 24 |
| 2021-11-20 | 12:00 | RC Eemland CU 1 | Cas RC CU 1 | Sportpark De Bokkeduinen. AMERSFOORT | 33 - 17 |
| 2021-11-20 | 13:00 | RC Hilversum CU 1 | RC Bulldogs CU 1 | Sportpark Berestein. Hilversum | 20 - 48 |
| 2021-12-11 | 11:00 | Cas RC CU 1 | CL RCW/Zaandijk CU 1 | Sportpark Wouterland. CASTRICUM | afgelast |
| 2021-12-11 | 11:00 | CL Amsterdam CU 1 | RC Hilversum CU 1 | Amsterdam | afgelast |
| 2021-12-11 | 12:00 | RC Eemland CU 1 | RC Bulldogs CU 1 | Sportpark De Bokkeduinen. AMERSFOORT | afgelast |
| 2021-12-18 | 11:00 | RC Bulldogs CU 1 | CL Amsterdam CU 1 | Fanny Blankers-Koen Sportpark. ALMERE | afgelast |
| 2021-12-18 | 11:00 | RC Hilversum CU 1 | Cas RC CU 1 | Sportpark Berestein. Hilversum | afgelast |
| 2021-12-18 | 11:00 | CL RCW/Zaandijk CU 1 | RC Eemland CU 1 | PURMEREND | afgelast |