| 2021-11-06 | 12:00 | HRC CU 1 | RC DIOK CU 1 | Haagsche Rugby Club. DEN HAAG | 15 - 7 |
| 2021-11-06 | 12:00 | Amstelveense RC CU 1 | RC The Dukes CU 1 | Sportpark Sportlaan West. AMSTELVEEN | 33 - 24 |
| 2021-11-06 | 12:00 | RRC CU 1 | RFC Haarlem CU 1 | Sportcomplex Duivensteijn. ROTTERDAM | 7 - 63 |
| 2021-11-13 | 11:00 | RFC Haarlem CU 1 | HRC CU 1 | Van der Aart Sportpark. HAARLEM | 12 - 24 |
| 2021-11-13 | 12:00 | RC DIOK CU 1 | Amstelveense RC CU 1 | RC DIOK. LEIDEN | 26 - 14 |
| 2021-11-20 | 11:00 | Amstelveense RC CU 1 | RRC CU 1 | Sportpark Sportlaan West. AMSTELVEEN | 64 - 0 |
| 2021-11-20 | 12:00 | HRC CU 1 | RC The Dukes CU 1 | Haagsche Rugby Club. DEN HAAG | 19 - 0 |
| 2021-11-20 | 12:15 | RC DIOK CU 1 | RFC Haarlem CU 1 | RC DIOK. LEIDEN | 35 - 7 |
| 2021-11-27 | 11:30 | RC The Dukes CU 1 | RRC CU 1 | RUGBYCLUB THE DUKES. 'S - HERTOGENBOSCH | 63 - 14 |
| 2021-12-11 | 11:00 | RC The Dukes CU 1 | RC DIOK CU 1 | RUGBYCLUB THE DUKES. 'S - HERTOGENBOSCH | afgelast |
| 2021-12-11 | 12:00 | RRC CU 1 | HRC CU 1 | Sportcomplex Duivensteijn. ROTTERDAM | afgelast |
| 2021-12-11 | 13:30 | Amstelveense RC CU 1 | RFC Haarlem CU 1 | Sportpark Sportlaan West. AMSTELVEEN | afgelast |
| 2021-12-18 | 11:00 | RC DIOK CU 1 | RRC CU 1 | RC DIOK. LEIDEN | afgelast |
| 2021-12-18 | 11:00 | RFC Haarlem CU 1 | RC The Dukes CU 1 | Van der Aart Sportpark. HAARLEM | afgelast |
| 2021-12-18 | 12:00 | HRC CU 1 | Amstelveense RC CU 1 | Haagsche Rugby Club. DEN HAAG | afgelast |