| 2022-01-29 | 11:30 | RC The Dukes CU 1 | URC CU 1 | RUGBYCLUB THE DUKES. 'S - HERTOGENBOSCH | 30 - 19 |
| 2022-01-29 | 13:00 | RC DIOK CU 1 | HRC CU 1 | RC DIOK. LEIDEN | 5 - 36 |
| 2022-01-29 | 13:00 | RFC Haarlem CU 1 | Amstelveense RC CU 1 | Van der Aart Sportpark. HAARLEM | 27 - 0 |
| 2022-02-05 | 12:00 | Amstelveense RC CU 1 | RC The Dukes CU 1 | Sportpark Sportlaan West. AMSTELVEEN | 19 - 10 |
| 2022-02-05 | 12:00 | HRC CU 1 | RFC Haarlem CU 1 | Haagsche Rugby Club. DEN HAAG | 5 - 0 |
| 2022-02-05 | 13:00 | URC CU 1 | RC DIOK CU 1 | Sportpark Rijnvliet. UTRECHT | 14 - 10 |
| 2022-02-12 | 10:00 | Amstelveense RC CU 1 | URC CU 1 | Sportpark Sportlaan West. AMSTELVEEN | 19 - 12 |
| 2022-02-12 | 11:00 | RFC Haarlem CU 1 | RC DIOK CU 1 | Van der Aart Sportpark. HAARLEM | 22 - 12 |
| 2022-02-12 | 11:00 | RC The Dukes CU 1 | HRC CU 1 | RUGBYCLUB THE DUKES. 'S - HERTOGENBOSCH | 5 - 43 |
| 2022-02-19 | 12:00 | RC DIOK CU 1 | RC The Dukes CU 1 | RC DIOK. LEIDEN | 31 - 5 |
| 2022-02-19 | 12:00 | RFC Haarlem CU 1 | URC CU 1 | Van der Aart Sportpark. HAARLEM | 22 - 7 |
| 2022-03-12 | 11:00 | RC The Dukes CU 1 | RFC Haarlem CU 1 | RUGBYCLUB THE DUKES. 'S - HERTOGENBOSCH | 12 - 10 |
| 2022-03-12 | 12:00 | Amstelveense RC CU 1 | RC DIOK CU 1 | Sportpark Sportlaan West. AMSTELVEEN | 43 - 5 |
| 2022-03-12 | 13:00 | URC CU 1 | HRC CU 1 | Sportpark Rijnvliet. UTRECHT | 0 - 48 |
| 2022-03-13 | 11:00 | HRC CU 1 | Amstelveense RC CU 1 | Haagsche Rugby Club. DEN HAAG | 12 - 17 |
| 2022-03-19 | 12:00 | Amstelveense RC CU 1 | RFC Haarlem CU 1 | Sportpark Sportlaan West. AMSTELVEEN | 39 - 17 |
| 2022-03-19 | 12:00 | HRC CU 1 | RC DIOK CU 1 | Haagsche Rugby Club. DEN HAAG | 32 - 5 |
| 2022-03-19 | 14:00 | URC CU 1 | RC The Dukes CU 1 | Sportpark Rijnvliet. UTRECHT | 22 - 7 |
| 2022-03-26 | 12:00 | RC The Dukes CU 1 | Amstelveense RC CU 1 | RUGBYCLUB THE DUKES. 'S - HERTOGENBOSCH | 5 - 31 |
| 2022-03-26 | 12:30 | RC DIOK CU 1 | URC CU 1 | De Vliet, Voorschoterweg 8c, LEIDEN | 27 - 24 |
| 2022-03-26 | 13:00 | RFC Haarlem CU 1 | HRC CU 1 | Van der Aart Sportpark. HAARLEM | 12 - 12 |
| 2022-04-02 | 12:00 | HRC CU 1 | RC The Dukes CU 1 | Haagsche Rugby Club. DEN HAAG | 41 - 0 |
| 2022-04-02 | 12:00 | RC DIOK CU 1 | RFC Haarlem CU 1 | RC DIOK. LEIDEN | 12 - 22 |
| 2022-04-02 | 12:30 | URC CU 1 | Amstelveense RC CU 1 | Sportpark Rijnvliet. UTRECHT | 0 - 27 |
| 2022-04-09 | 10:30 | RFC Haarlem CU 1 | URC CU 1 | Van der Aart Sportpark. HAARLEM | 47 - 0 |
| 2022-04-09 | 11:00 | Amstelveense RC CU 1 | HRC CU 1 | Sportpark Sportlaan West. AMSTELVEEN | 7 - 12 |
| 2022-04-09 | 11:30 | RC The Dukes CU 1 | RC DIOK CU 1 | RUGBYCLUB THE DUKES. 'S - HERTOGENBOSCH | 43 - 12 |
| 2022-04-23 | 12:00 | RFC Haarlem CU 1 | RC The Dukes CU 1 | Van der Aart Sportpark. HAARLEM | 55 - 0 |
| 2022-04-23 | 12:00 | HRC CU 1 | URC CU 1 | Haagsche Rugby Club. DEN HAAG | 48 - 5 |
| 2022-04-23 | 12:00 | RC DIOK CU 1 | Amstelveense RC CU 1 | RC DIOK. LEIDEN | 5 - 12 |