| 2022-01-29 | 11:00 | RC DIOK JU 1 | RFC Haarlem JU 1 | RC DIOK. LEIDEN | 17 - 24 |
| 2022-01-29 | 12:00 | BRC JU 1 | CL Amsterdam JU 1 | Sportboulevard Wisselaar. BREDA | 48 - 0 |
| 2022-01-29 | 12:30 | RC Eemland JU 1 | HRC JU 2 | Sportpark De Bokkeduinen. AMERSFOORT | 32 - 15 |
| 2022-02-05 | 12:00 | CL Amsterdam JU 1 | RC DIOK JU 1 | De Eendracht. AMSTERDAM | 7 - 33 |
| 2022-02-05 | 13:00 | HRC JU 2 | BRC JU 1 | Haagsche Rugby Club. DEN HAAG | 22 - 8 |
| 2022-02-12 | 12:00 | RFC Haarlem JU 1 | HRC JU 2 | Van der Aart Sportpark. HAARLEM | 26 - 5 |
| 2022-02-12 | 13:00 | RC DIOK JU 1 | BRC JU 1 | RC DIOK. LEIDEN | 19 - 17 |
| 2022-02-12 | 13:15 | RC Eemland JU 1 | CL Amsterdam JU 1 | Sportpark De Bokkeduinen. AMERSFOORT | 56 - 12 |
| 2022-02-17 | 19:00 | RFC Haarlem JU 1 | RC Eemland JU 1 | Van der Aart Sportpark. HAARLEM | 19 - 15 |
| 2022-02-19 | 12:00 | BRC JU 1 | RC Eemland JU 1 | Sportboulevard Wisselaar. BREDA | 22 - 14 |
| 2022-02-19 | 13:00 | RC DIOK JU 1 | HRC JU 2 | RC DIOK. LEIDEN | 12 - 27 |
| 2022-03-05 | 12:00 | CL Amsterdam JU 1 | RFC Haarlem JU 1 | De Eendracht. AMSTERDAM | 0 - 55 |
| 2022-03-12 | 12:00 | RFC Haarlem JU 1 | BRC JU 1 | Van der Aart Sportpark. HAARLEM | 19 - 8 |
| 2022-03-12 | 13:00 | HRC JU 2 | CL Amsterdam JU 1 | Haagsche Rugby Club. DEN HAAG | 62 - 19 |
| 2022-03-12 | 13:15 | RC Eemland JU 1 | RC DIOK JU 1 | Sportpark De Bokkeduinen. AMERSFOORT | 38 - 21 |
| 2022-03-19 | 12:00 | CL Amsterdam JU 1 | BRC JU 1 | De Eendracht. AMSTERDAM | 7 - 44 |
| 2022-03-19 | 12:00 | RFC Haarlem JU 1 | RC DIOK JU 1 | Van der Aart Sportpark. HAARLEM | 29 - 5 |
| 2022-03-19 | 13:00 | HRC JU 2 | RC Eemland JU 1 | Haagsche Rugby Club. DEN HAAG | 15 - 29 |
| 2022-03-26 | 13:15 | RC Eemland JU 1 | RFC Haarlem JU 1 | Sportpark De Bokkeduinen. AMERSFOORT | 24 - 46 |
| 2022-03-26 | 13:15 | RC DIOK JU 1 | CL Amsterdam JU 1 | RC DIOK. LEIDEN | 30 - 0 |
| 2022-04-02 | 12:00 | CL Amsterdam JU 1 | RC Eemland JU 1 | Amsterdam | 0 - 74 |
| 2022-04-02 | 12:00 | BRC JU 1 | RC DIOK JU 1 | Sportboulevard Wisselaar. BREDA | 14 - 24 |
| 2022-04-02 | 13:00 | HRC JU 2 | RFC Haarlem JU 1 | Haagsche Rugby Club. DEN HAAG | 0 - 33 |
| 2022-04-06 | 19:15 | BRC JU 1 | HRC JU 2 | Sportboulevard Wisselaar. BREDA | 15 - 26 |
| 2022-04-09 | 12:45 | RFC Haarlem JU 1 | CL Amsterdam JU 1 | Van der Aart Sportpark. HAARLEM | 60 - 0 |
| 2022-04-09 | 13:00 | HRC JU 2 | RC DIOK JU 1 | Haagsche Rugby Club. DEN HAAG | 0 - 27 |
| 2022-04-09 | 13:30 | RC Eemland JU 1 | BRC JU 1 | Sportpark De Bokkeduinen. AMERSFOORT | 31 - 10 |
| 2022-04-23 | 12:00 | CL Amsterdam JU 1 | HRC JU 2 | De Eendracht. AMSTERDAM | 5 - 35 |
| 2022-04-23 | 12:00 | BRC JU 1 | RFC Haarlem JU 1 | Sportboulevard Wisselaar. BREDA | 7 - 19 |
| 2022-04-23 | 13:15 | RC DIOK JU 1 | RC Eemland JU 1 | RC DIOK. LEIDEN | 36 - 7 |